Abemaxen 200 Tablets — Abemaciclib 200 mg (60 Tabs) Everest
Abemaxen 200 mg (Abemaciclib) is a high-strength targeted CDK4/6 inhibitor and a generic equivalent to Verzenio. It works by blocking the enzymes that drive cancer cell division. This specific 200 mg strength is primarily indicated for use as monotherapy (treatment without concurrent hormonal therapy) in advanced stages of breast cancer.
Manufacturer: Everest Pharmaceuticals (Bangladesh). It offers a continuous dosing schedule to maintain constant pressure on tumor cells.
Key Features:
- ✅ Monotherapy Option: Designed for patients who have exhausted hormonal and chemotherapy options.
- ✅ Cell Cycle Control: Arrests tumor growth by inhibiting cell replication.
- ✅ Convenient Dosing: The 200 mg tablet simplifies the regimen for patients requiring higher doses.
Prescribed by oncologists specifically for the treatment of adult patients with:
- 🔹 HR+/HER2- Advanced or Metastatic Breast Cancer:
- As monotherapy for patients with disease progression following endocrine therapy and prior chemotherapy in the metastatic setting.
Sales Unit: Box containing 60 film-coated tablets (200 mg strength). This constitutes exactly a 30-day supply.
⚠️ APPLICATION INSTRUCTIONS:
- Standard Dosage (Monotherapy): 200 mg (one tablet) taken orally twice daily.
- Administration: Take at approximately the same time every morning and evening. Swallow whole with water. Can be taken with or without food. Do not chew, crush, or split.
- 🚫 Dietary Restriction: Do not consume grapefruit or grapefruit juice during treatment.
- ✋ Missed Dose: If a dose is missed or vomiting occurs, skip it and take the next dose at the scheduled time. Do not double up.
- ⛔ Pregnancy & Breastfeeding: Strictly contraindicated due to fetal toxicity.
- Hypersensitivity to Abemaciclib.
- Severe hepatic impairment (requires dose reduction).
- End-stage renal disease.
Regular monitoring of complete blood count (CBC) and liver function is mandatory. Potential side effects include:
- 🚽 Diarrhea: Very common. Manage with antidiarrheal medication and hydration immediately upon onset.
- 🩸 Hematologic: Neutropenia (low white blood cells), anemia, thrombocytopenia.
- 🤢 Gastrointestinal: Nausea, vomiting, abdominal pain, decreased appetite.
- 💤 General: Fatigue, weakness.
- 🔶 Hepatotoxicity: Elevated liver enzymes (ALT/AST).
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