Active ingredient
Manufacturer
Everest
Trifluxen β Trifluridine and Tipiracil 15 mg + 6.14 mg Tablets
20191β΄
21947β΄
-8%
Trifluxen (Trifluridine and Tipiracil) is a combination antitumor drug and a generic equivalent to Lonsurf. It is an oral chemotherapy agent used to treat advanced forms of digestive system cancers that have become resistant to other treatments.
Manufacturer: Everest Pharmaceuticals (Bangladesh). β οΈ Note: Contains 30 tablets per bottle. Each tablet contains 15 mg of Trifluridine and 6.14 mg of Tipiracil.
Key Features:
- β Dual Action Mechanism: Trifluridine inhibits cancer cell growth by interfering with DNA function, while Tipiracil prevents the breakdown of Trifluridine, maintaining effective blood levels.
- β Survival Benefit: Proven to extend overall survival in patients with metastatic cancer refractory to standard chemotherapy.
- β Accessibility: A high-quality generic from Everest making essential oncology care more affordable.
Prescribed by oncologists for patients with disease progression following prior therapies:
- πΉ Metastatic Colorectal Cancer (mCRC): For patients previously treated with fluoropyrimidine-, oxaliplatin-, and irinotecan-based chemotherapy.
- πΉ Metastatic Gastric Cancer or Gastroesophageal Junction Adenocarcinoma.
Sales Unit: 1 Bottle (30 Tablets, 15 mg / 6.14 mg).
β οΈ COMPLEX DOSING SCHEDULE (Cycles):
- Dose Calculation: The exact number of tablets is determined by the doctor based on the patient's Body Surface Area (BSA).
- Cycle Schedule (28 days): Typically taken for 5 days, followed by 2 days rest, then 5 days taken, followed by 14 days rest.
- Frequency: Taken twice daily (morning and evening).
- π½οΈ Administration: Must be taken within 1 hour AFTER completion of a meal with water. Do not take on an empty stomach.
- Safety: Wash hands after handling. Pregnant women should not handle the tablets.
- β Severe Renal or Hepatic Impairment: Requires strict monitoring and potential dose adjustment.
- Pregnancy and breastfeeding (harmful to the fetus).
- Children (under 18 years of age).
- Hypersensitivity to active substances.
Regular Complete Blood Counts (CBC) are mandatory during therapy. Potential side effects:
- π©Έ Bone Marrow Suppression: Neutropenia (infection risk), anemia (fatigue), thrombocytopenia (bleeding risk).
- π Gastrointestinal: Nausea, vomiting, diarrhea, loss of appetite.
- π General: Severe fatigue, weakness.
- Seek immediate medical attention if fever or signs of infection occur!
Active ingredient
Manufacturer
Everest
100% original product
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