Nab Paclitero (Nab-Paclitaxel) 100 mg
NAB PACLITERO (Nab-Paclitaxel 100 mg) is a cutting-edge nanotechnology chemotherapy drug. It is a generic equivalent of Abraxane.
Manufacturer: Hetero Healthcare.
The "Solvent-Free" Advantage:
Standard Paclitaxel is dissolved in toxic solvents (Cremophor EL) that cause severe allergic reactions. NAB PACLITERO uses human albumin (protein) nanotechnology to deliver the drug. This eliminates the need for toxic solvents, allowing for higher doses with fewer side effects and deeper tumor penetration.
✅ Key Benefit: No risk of solvent-based hypersensitivity reactions. Acts like a "Trojan Horse," using the body's natural protein transport to enter cancer cells.
Indicated for the treatment of:
- 🎗️ Metastatic Breast Cancer: For patients who have failed first-line chemotherapy.
- 🦀 Metastatic Pancreatic Cancer: Used in combination with Gemcitabine as a first-line treatment.
- 🫁 Non-Small Cell Lung Cancer (NSCLC): For patients who are not candidates for curative surgery or radiation therapy.
Form: Lyophilized powder for Injectable Suspension (100 mg).
⚠️ ADMINISTRATION WARNINGS:
- No Premedication: Unlike standard Paclitaxel, corticosteroids and antihistamines are generally not required before infusion.
- Infusion Time: Rapid 30-minute IV infusion.
- 🚫 DO NOT USE FILTERS: Standard infusion sets with in-line filters must not be used, as they will block the albumin nanoparticles.
- Baseline neutrophil count < 1,500 cells/mm³.
- Severe hepatic impairment.
- Pregnancy and breastfeeding.
Common side effects include:
- Neuropathy: Numbness or tingling in hands and feet (sensory neuropathy).
- Bone Marrow Suppression: Neutropenia (low white blood cells), anemia.
- Alopecia: Hair loss.
- Fatigue and nausea.
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