Cerixen Capsules — Ceritinib 150 mg (90 Caps) Everest
Cerixen 150 mg (Ceritinib) is a potent targeted therapy and an inhibitor of anaplastic lymphoma kinase (ALK), serving as a generic equivalent to Zykadia. It works by blocking the action of the abnormal ALK protein that causes cancer cells to grow and divide. It is particularly valuable for patients who have developed resistance to prior therapies like crizotinib.
Manufacturer: Everest Pharmaceuticals (Bangladesh). Designed specifically for ALK-positive lung cancer patients.
Key Features:
- ✅ Second-Generation ALK Inhibitor: Provides a treatment option when first-line therapies fail.
- ✅ Targeted Precision: Specifically inhibits ALK phosphorylation, halting tumor proliferation.
- ✅ Optimized Regimen: The 150 mg capsule formulation allows for dosing with food, improving gastrointestinal tolerability.
Prescribed by oncologists for the treatment of adult patients with:
- 🔹 Non-Small Cell Lung Cancer (NSCLC): Metastatic ALK-positive NSCLC as detected by an FDA-approved test.
Sales Unit: Bottle in a box containing 90 capsules (150 mg strength). This provides exactly a 30-day supply.
⚠️ APPLICATION INSTRUCTIONS:
- Standard Dosage: 450 mg (three 150 mg capsules) taken orally once daily.
- Administration: Take with food. Swallow capsules whole with water. Taking with food improves absorption and reduces stomach upset.
- Dietary Warning: Avoid grapefruit and grapefruit juice, as they can dangerously increase drug levels in the blood. Do not chew or crush capsules.
- ✋ Missed Dose: Make up the dose unless the next scheduled dose is within 12 hours.
- ⛔ Pregnancy & Breastfeeding: Strictly contraindicated. Effective contraception is required during treatment and for 3 months after.
- Hypersensitivity to Ceritinib.
- Congenital Long QT Syndrome.
- Severe hepatic impairment requires dose adjustment.
Monitoring of liver enzymes, fasting glucose, and ECG is required. Potential side effects include:
- 🤢 Gastrointestinal: Diarrhea, nausea, vomiting (very common). Taking with food mitigates severity.
- 🔶 Hepatotoxicity: Elevated liver enzymes (ALT/AST).
- 🥗 Metabolic: Hyperglycemia (high blood sugar), decreased appetite.
- ❤️ Cardiac: Bradycardia (slow heart rate), QT prolongation.
- 💤 General: Fatigue, rash.
What Customers Say
No reviews yet
Your review can be the first!