Tenvir (Tenofovir Disoproxil) 300 mg Tablets (30 Count)
Tenvir is a widely used antiretroviral medication. Active ingredient: Tenofovir Disoproxil Fumarate (TDF) 300 mg.
Manufacturer: Cipla (India). A high-quality generic equivalent of the originator brand Viread.
Mechanism of Action:
Tenvir belongs to the class of Nucleotide Reverse Transcriptase Inhibitors (NRTIs). It works by blocking the reverse transcriptase enzyme, preventing the virus from multiplying. It remains a cornerstone therapy in many global treatment protocols due to its proven high potency.
✅ Note: Effective but requires monitoring of renal function.
Indicated for the treatment of:
- Chronic Hepatitis B: For effective viral suppression in adults and adolescents (12+).
- HIV-1 Infection: Must be used in combination with other antiretroviral agents. Not to be used alone for HIV treatment.
Standard Dosage: One tablet (300 mg) once daily.
⚠️ Administration Guide:
- 🍲 Take with food. A high-fat meal increases the drug's bioavailability.
- Adherence is crucial: Take it at the same time every day.
- Renal Adjustment: Dosing interval adjustment is required for patients with Creatinine Clearance < 50 mL/min.
- Severe renal impairment (without dose adjustment).
- History of bone disease (osteomalacia/osteoporosis).
- Breastfeeding.
- Hypersensitivity to Tenofovir.
Long-term use requires monitoring:
- Renal Toxicity: Can cause kidney damage. Regular monitoring of Serum Creatinine and Phosphorus is mandatory.
- Bone Density Loss: May decrease bone mineral density. Supplementation with Calcium and Vitamin D is often advised.
- Gastrointestinal issues (Flatulence, Nausea).
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