Olestar Sachets — Cholestyramine 4 gm (10 Sachets) Everest
Olestar 4 gm (Cholestyramine Resin Anhydrous USP) is a bile acid sequestrant. It is not absorbed into the bloodstream; instead, it works locally in the intestines by binding to bile acids and removing them from the body. This process forces the liver to convert blood cholesterol into new bile acids, effectively lowering "bad" LDL cholesterol levels.
Manufacturer: Everest Pharmaceuticals. This medication comes as a powder for oral suspension and features a pleasant mango flavor, making it easier and more palatable to consume.
Key Features:
- ✅ Cholesterol Reduction: Effectively lowers LDL cholesterol in the blood, reducing cardiovascular risks.
- ✅ Pruritus Relief: Rapidly alleviates severe itching caused by bile stasis in liver diseases.
- ✅ Digestive Normalization: Widely used to treat bile acid diarrhea (often experienced after gallbladder removal or in conditions like Crohn's disease).
Prescribed by a physician (cardiologist, gastroenterologist, or hepatologist) for the following conditions:
- 🔹 Hypercholesterolemia: Primary hypercholesterolemia (as an adjunct to diet for the reduction of elevated serum cholesterol).
- 🔹 Pruritus: Itching associated with partial biliary obstruction or primary biliary cirrhosis.
- 🔹 Bile Acid Diarrhea: Chronic diarrhea associated with bile acid malabsorption (e.g., post-cholecystectomy syndrome, short bowel syndrome).
Sales Unit: Carton box containing 10 sachets of powder for oral suspension. Strength: 4 grams of Cholestyramine per sachet.
⚠️ APPLICATION INSTRUCTIONS:
- ⛔ STRICTLY PROHIBITED: Never take the dry powder alone (it may provoke choking or esophageal spasm)!
- Preparation: Pour the contents of 1 sachet into a glass (100-150 ml) of water, juice, or mix with highly fluid soups or pulpy fruits (like applesauce). Stir vigorously to create a uniform suspension.
- Standard Dosage: Typically starts with 1 sachet 1 to 2 times daily. The dose may be increased by a doctor if necessary (up to 4-6 sachets per day).
- ✋ Crucial Drug Interaction Rule: Cholestyramine can bind to other medications and prevent their absorption. Take other drugs at least 1 hour before or 4 to 6 hours after taking Olestar.
- ⛔ Complete Biliary Obstruction: Ineffective if no bile is secreted into the intestine.
- Bowel obstruction.
- Hypersensitivity to Cholestyramine or any excipients.
- Pregnancy and breastfeeding (use with caution, as it may interfere with the absorption of fat-soluble vitamins).
Because it is not absorbed systemically, side effects are primarily gastrointestinal:
- 💩 Gastrointestinal: Constipation is the most common side effect (patients should increase fluid and fiber intake). Also bloating, flatulence, nausea.
- 🩸 Vitamin Deficiency: Long-term use of high doses may interfere with the absorption of fat-soluble vitamins (A, D, E, K).
- 🛡️ Other: Perianal irritation (rarely).
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