Tivoxen β Tivozanib 1.34 mg Capsules
9218β΄
10096β΄
-9%
Tivoxen 1.34 mg (Tivozanib) is a highly potent targeted therapy for kidney cancer and a generic equivalent to Fotivda. It is an oral vascular endothelial growth factor receptor (VEGFR) tyrosine kinase inhibitor designed to starve the tumor of its blood supply.
Manufacturer: Everest Pharmaceuticals (Bangladesh). β οΈ Note: Contains 21 capsules per bottle. This quantity corresponds exactly to the active treatment phase of one cycle.
Key Features:
- β Angiogenesis Inhibitor: Blocks the formation of new blood vessels that tumors need to grow and spread.
- β High Selectivity: Specifically targets all three VEGFR receptors with a long half-life, aiming for consistent efficacy with potentially fewer off-target side effects.
- β Accessibility: Provides a cost-effective option for advanced renal cell carcinoma treatment compared to the original brand.
Prescribed by oncologists for the treatment of adult patients with:
- πΉ Relapsed or Refractory Advanced Renal Cell Carcinoma (RCC): Specifically following two or more prior systemic therapies.
- πΉ Used as a third or fourth-line treatment option.
Sales Unit: 1 Bottle (21 Capsules of 1.34 mg).
β οΈ CYCLICAL DOSING SCHEDULE:
- Standard Regimen: Take 1 capsule (1.34 mg) once daily for 21 consecutive days.
- Rest Period: Followed by 7 days off treatment. The complete cycle is 28 days.
- Administration: Swallow the capsule whole with water. Can be taken with or without food.
- Missed Dose: If a dose is missed, do not take an extra dose. Take the next dose at your regular time the next day.
- β Pregnancy and Breastfeeding: Can cause fetal harm.
- Severe hepatic impairment.
- Children (under 18 years of age).
- Hypersensitivity to Tivozanib or tartrazine dye.
- Concomitant use of strong CYP3A4 inducers (may reduce efficacy).
Blood pressure monitoring is essential during therapy. Potential side effects:
- π©Έ Cardiovascular: Hypertension (high blood pressure) β very common.
- π Gastrointestinal & General: Diarrhea, nausea, decreased appetite, fatigue.
- π£οΈ Dysphonia: Voice changes or hoarseness.
- π§ͺ Hypothyroidism (thyroid dysfunction).
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