Bdenza (Enzalutamide) 40 mg
11433₴
12752₴
-10%
Bdenza is a next-generation anti-androgen medication used to treat advanced prostate cancer. Active ingredient: Enzalutamide (40 mg).
Manufacturer: BDR Pharmaceuticals (India). It is a cost-effective generic version of the brand drug Xtandi.
Key Advantages over Abiraterone (Zytiga):
- ✅ No Steroids Required: Unlike Abiraterone, Bdenza does not require co-administration with prednisone, avoiding steroid-related side effects.
- ✅ Flexible Dosing: Can be taken with or without food.
- ✅ Triple Mechanism: Inhibits androgen binding, prevents nuclear translocation, and blocks DNA binding.
Treatment of metastatic castration-resistant prostate cancer (mCRPC) and metastatic castration-sensitive prostate cancer (mCSPC).
It is indicated for:
- Patients who have not yet received chemotherapy (asymptomatic or mildly symptomatic).
- Patients whose disease has progressed on or after docetaxel therapy.
Recommended Daily Dose: 160 mg once daily.
💊 Since each capsule contains 40 mg, you must take 4 capsules at once.
Administration:
- Take orally with or without food.
- Swallow capsules whole with water. Do not chew, dissolve, or open the capsules.
- Take at the same time each day.
- Hypersensitivity to Enzalutamide.
- History of Seizures: Use with caution in patients with a history of seizures or predisposing factors (brain injury, stroke), as the drug may lower the seizure threshold.
- Women who are or may become pregnant.
Generally well-tolerated compared to chemotherapy. Common side effects include:
- Fatigue (Asthenia) — most common.
- Hot flushes.
- Headache.
- Hypertension (High blood pressure).
- Increased risk of falls or fractures.
Seizure Risk: Discontinue permanently if a seizure occurs during treatment.
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